Application of weighted risk scores to estimate the relative contribution of environmental and genetic factors to skin aging: A step towards individualized cosmetics

Dr. Claudia Wigmann from Leibniz Research Institute for Environmental Medicine, Germany will give presentation entitled “Application of weighted risk scores to estimate the relative contribution of environmental and genetic factors to skin aging: A step towards individualized cosmetics” during  Porto Skin Ageing & Challenges Congress 2019 which will be held in Porto, on February 25-27, 2019.

Short summary of talk: “Skin aging is influenced by environmental factors including solar radiation, air pollution, tobacco smoke and nutritional habits as well as by genetic factors, but the relative contribution of each of these factors is currently unknown.

We addressed this question using weighted risk scores to assess the relative importance of these factors for two prominent skin aging traits: coarse facial wrinkles and facial lentigines.

Employing this model, we found that all risk scores combined explain 24% of the variance of wrinkles and 27% of lentigines.

Among the environmental factors, relative contributions to wrinkles were ranked UVR > tobacco smoke > air pollution > nutritional habits, while in comparison to wrinkles the relative contributions to lentigines differed in ranking and magnitude (nutritional habits > air pollution > UVR > tobacco smoke).”

For more information: skin-challenges.com