Category: News & Media

Infrared Radiation: A Double-Edged Sword for Skin Health

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Researchers from University of California Irvine, University of Oklahoma and Henry Ford Medical Center have highlighted the complex effects of infrared radiation (IR) on human skin. The study explores both the detrimental and beneficial impacts of IR, providing a comprehensive overview of the current understanding of how this type of radiation influences skin health. Infrared radiation,…

Exploring New Mechanisms of Skin Aging: The Role of Mitophagy and Extracellular Vesicles

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A recent study by researchers from the University of Innsbruck, Austria, sheds new light on the mechanisms underlying skin aging, particularly in relation to mitochondrial quality control. Co-author Ines Martic will join the upcoming “Skin Ageing & Challenges” conference in November to present these innovative findings. The research addresses the two types of skin aging:…

Next-Generation Artificial Skin: Advancing Tactile Sensation and Promoting Wound Healing

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Overall schematic of the WTSA and converted tactile signal transfer process to stimulate the sciatic nerve. A new study published in Nature Communications has revealed an innovative advancement in skin regeneration and sensory restoration. Researchers have developed the Wireless Powered Tactile Sensory System Embedded Artificial Skin (WTSA), a novel technology designed to address severe skin…

Innovative Diagnostics: How Facial Temperature Could Transform Early Metabolic Disease Detection

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Average facial temperatures of three aging-status groups among women 50-60 years old. Credit: Zhengqing Yu and Jing-Dong J Han. Dr. Jing-Jong Han will join Skin Ageing & Challenges 2024 this November to discuss her latest findings on the innovative thermal imaging techniques for detecting aging disorders with a focus on the “ThermaFace Method”. Join us…

Metformin-Engineered Extracellular Vesicles: Strategic Role in Aging Skin Repair

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Schematic diagram shows the Met-EV–mediated biological performance. Met-EV could mediate the activation of mitophagy, rescue of mitochondria, and reprogramming of energy metabolism in fibroblasts.   Researchers from the Shanghai Jiao Tong University School of Medicine have discovered a novel approach to enhancing the repair of aging skin, a common issue marked by impaired wound healing…

Iron Metabolism in Skin: Implications for Skin Ageing and Health

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Schematic depiction of the iron metabolism in the epidermis. The process of keratinocyte differentiation is represented by cells in the basal layer, the granular layer and the cornified layer. The distribution of iron-binding proteins and regulators of iron metabolism and transport is shown according to the evidence and hypotheses discussed in the main text. Alternative…

Cellular Senescence: Novel Interventions for Combating Skin Aging

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Hallmarks of skin aging. An illustration of skin senescent cell accumulation and corresponding senescence-associated secretory phenotype (SASP) factor release in young versus old human skin models. Researchers from the Mayo Clinic, led by Dr. Saranya Wyles, have shed new light on the complex processes of skin aging, emphasizing the critical role of cellular senescence. As…
The hallmarks of aging as a conceptual framework for health and longevity research

The hallmarks of aging as a conceptual framework for health and longevity research

Posted on by skin_challenges
In a comprehensive review led by José M. P. Freije from the Universidad de Oviedo, Spain, the transformative impact of The Hallmarks of Aging framework in understanding longevity was explored in depth. Originally proposed in 2013 and recently updated to include three new hallmarks, this framework categorizes aging into primary, antagonistic, and integrative factors, offering…

Mitochondrial Quality Control: Key to Addressing Skin Aging

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Graphical Abstract: The homeostasis of mitochondrial quality helps to ameliorate skin aging caused by internal and external factors. Credits: Chang Zhang et al., 2023. Researchers from Jilin University, China, led by Dr. Xu He, have published a review shedding new light on skin aging and mitochondria. Their findings highlight the critical role of mitochondrial quality…