A Novel Hybrid Artificial Neural Network Technique for the Early Skin Cancer Diagnosis

A Novel Hybrid Artificial Neural Network Technique for the Early Skin Cancer Diagnosis

Tajjour et al. used an innovative hybrid machine learning-technique for the early skin cancer diagnosis fusing Convolutional Neural Network and Multilayer Perceptron to analyze images and information related to the skin cancer. This information is extracted manually after applying different color space conversions on the original images for better screening of the lesions. The proposed…
Posted on March 16, 2023
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Can algae enhance skin regeneration and wound healing?

Can algae enhance skin regeneration and wound healing?

Schematic of EMVEG encapsulating protein and lipid layer fragments and its confocal microscopy images of β-glucan and lipids labeled aniline blue (blue colored) and Texas red-DHPE (red colored), respectively A product of a freshwater single-celled green algae called Euglena gracilis may enhance skin regeneration to speed up wound healing, according to new research published in Advanced…
Posted on January 30, 2023
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Scientists develop novel mRNA delivery method using extracellular vesicles

Scientists develop novel mRNA delivery method using extracellular vesicles

Representative Masson trichrome collagen staining of the epidermis, dermis and subcutis for all mouse groups.  A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs). The new technique has the potential to overcome many of the delivery hurdles faced…
Posted on January 27, 2023
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Getting under your skin for better health

Getting under your skin for better health

A prototype of a device that can measure interstitial fluid uses microneedles.  The next frontier of continuous health monitoring could be skin deep. Biomedical engineers at the University of Cincinnati say interstitial fluid, the watery fluid found between and around cells, tissues or organs in the body, could provide an excellent medium for early disease…
Posted on January 27, 2023
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A Novel Sprayable Treatment for Wound Healing

A Novel Sprayable Treatment for Wound Healing

Liu et al. established a novel sprayable adhesive (ZnMet-PF127) by the combination of a thermosensitive hydrogel (Pluronic F127, PF127) and a coordination complex of zinc and metformin (ZnMet).  They demonstrated that ZnMet-PF127 potently promotes the healing of traumatic skin defect and burn skin injury by promoting cell proliferation, angiogenesis, collagen formation. ZnMet also turned out…
Posted on January 6, 2023
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“Unexpected” – Scientists Discover an Anti-Aging Mechanism

“Unexpected” – Scientists Discover an Anti-Aging Mechanism

The mechanism extends the life of the immune system.  A multinational team headed by University College London scientists has discovered a new mechanism that slows down and maybe even prevents the normal aging of immune cells, one of the nine “hallmarks of aging.” The discovery in-vitro (cells) and validated in mice was “unexpected,” according to the researchers,…
Posted on November 9, 2022
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Extracellular Vesicles Derived from Pinctada martensii Mucus Regulate Skin Inflammation

Extracellular Vesicles Derived from Pinctada martensii Mucus Regulate Skin Inflammation

Extracellular vesicles (EVs) and their exosome subsets are vesicle-like nanoparticles that are secreted by cells and contain various factors that treat various diseases. Wu et al.  isolated EVs from the marine shellfish Pinctada martensii mucus and studied the efficacy of those EVs in modulating the inflammatory environment. A human skin inflammatory cell model was established to…
Posted on October 11, 2022
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Sensory Neurons in Human Skin Play Key Role in Pigmentation

Sensory Neurons in Human Skin Play Key Role in Pigmentation

  News Release, Skin Ageing & challenges – 26 September 2022. Our skin forms the physical boundary between us and the outside world, yet it still holds a surprising number of secrets. Now, researchers from Japan have discovered that sensory nerve cells in our skin do more than just help us feel our way around.…
Posted on September 26, 2022
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Skin Microbiome Profile of Healthy Cameroonians and Japanese

Skin Microbiome Profile of Healthy Cameroonians and Japanese

  The commensal microbes of the skin have a significant impact on dermal physiology and pathophysiology. Racial and geographical differences in the skin microbiome are suggested and may play a role in the sensitivity to dermatological disorders, including infectious diseases. Little is known about the skin microbiome profiles of people living in Central Africa, where…
Posted on September 6, 2022
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In-cytoplasm Mitochondrial Transplantation for Stem Cells Engineering & Tissue Regeneration

In-cytoplasm Mitochondrial Transplantation for Stem Cells Engineering & Tissue Regeneration

Representative images of the wound area (left) and the corresponding fractions of wounds healed (right) by different treatments. News Release, Skin Aging & Challenges – August 31, 2022 Stem cell therapies are unsatisfactory due to poor cell survival and engraftment. Stem cells used for therapy must be properly “tuned” for a harsh in vivo environment.…
Posted on August 31, 2022
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