Category: News & Media

The analysis of the role of the mitochondria in oxidative damage and skin aging has been a significant aspect of dermatological research. Mitochondria generate most reactive oxygen species (ROS) which, in excess, are cytotoxic and DNA-damaging and promote (photo-)aging. However, ROS also possesses key physiological and regulatory functions and mitochondrial dysfunction is prominent in several…

The composition of the skin microbiome varies from infancy to adulthood and becomes most stable in adulthood. Adult acne patients harbour an ‘acne microbiome’ dominated by specific strains of Cutibacterium acnes. However, the precise timing of skin microbiome evolution, the development of the acne microbiome, and the shift to virulent C. acnes strain composition during puberty is unknown. Schneider…

Tajjour et al. used an innovative hybrid machine learning-technique for the early skin cancer diagnosis fusing Convolutional Neural Network and Multilayer Perceptron to analyze images and information related to the skin cancer. This information is extracted manually after applying different color space conversions on the original images for better screening of the lesions. The proposed…

Representative Masson trichrome collagen staining of the epidermis, dermis and subcutis for all mouse groups.  A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs). The new technique has the potential to overcome many of the delivery hurdles faced…

Liu et al. established a novel sprayable adhesive (ZnMet-PF127) by the combination of a thermosensitive hydrogel (Pluronic F127, PF127) and a coordination complex of zinc and metformin (ZnMet).  They demonstrated that ZnMet-PF127 potently promotes the healing of traumatic skin defect and burn skin injury by promoting cell proliferation, angiogenesis, collagen formation. ZnMet also turned out…