Category: News & Media

Skin Microbiome Profile of Healthy Cameroonians and Japanese

Posted on by skin_challenges
  The commensal microbes of the skin have a significant impact on dermal physiology and pathophysiology. Racial and geographical differences in the skin microbiome are suggested and may play a role in the sensitivity to dermatological disorders, including infectious diseases. Little is known about the skin microbiome profiles of people living in Central Africa, where…

In-cytoplasm Mitochondrial Transplantation for Stem Cells Engineering & Tissue Regeneration

Posted on by skin_challenges
Representative images of the wound area (left) and the corresponding fractions of wounds healed (right) by different treatments. News Release, Skin Aging & Challenges – August 31, 2022 Stem cell therapies are unsatisfactory due to poor cell survival and engraftment. Stem cells used for therapy must be properly “tuned” for a harsh in vivo environment.…
Skin rejuvenation

Topical Platelet Exosomes: New Strategy for Skin Rejuvenation

Posted on by skin_challenges
News release, Skin Ageing & Challenges – 23 June 2022 Exosomes are regenerative mediators for skin rejuvenation. In the context of aesthetic medicine, platelets are an ideal source for exosomal isolation given their role in skin healing. Human platelet extract (HPE) is an allogeneic exosome product derived from US-sourced, leukocyte-reduced apheresed platelets with consistent purity…

Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Against Photoaging

Posted on by skin_challenges
News Release, Skin Aging & Challenges – August 8, 2022 Oxidative stress and mitochondrial dysfunction play a role in the process of skin photoaging via activation of matrix metalloproteases (MMPs) and the subsequent degradation of collagen. The activation of nuclear factor E2-related factor 2 (Nrf2), a transcription factor controlling antioxidant and cytoprotective defense systems, might…
Skin Ageing

Skin Cells Made Up To 40 Years Younger with New “Rejuvenation” Technique

Posted on by skin_challenges
Aging is the gradual decline in cell and tissue function over time. It is characterized by various factors, including telomere attrition, genetic instability, and misfolded proteins. The progression of some age-related changes can be measured and used to predict age in humans. Induced pluripotent stem cell (iPSC) reprogramming is a process in which any cell can be converted into an…

In-vivo Skin Cancer Diagnosis via Real-Time High-Resolution Millimeter-Wave Imaging

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Schematic of the developed ultra-wideband millimeter-wave imaging system for real-time in-vivo skin cancer imaging. News Release, Skin Aging & Challenges – July 11, 2022 High-resolution millimeter-wave imaging (HR-MMWI), with its high discrimination contrast and sufficient penetration depth, can potentially provide affordable tissue diagnostic information noninvasively. Mirbeik et al. evaluated the application of a real-time system…

Extracellular Vesicles: Potential Theranostic Platforms for Skin Diseases and Aging

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Conceptual overview of EVs and their associated effects on skin News Release, Skin Aging & Challenges – July 8, 2022 Extracellular vesicles (EVs), naturally secreted by cells, act as mediators for communication between cells. They are transported to the recipient cells along with cargoes such as nucleic acids, proteins, and lipids that reflect the changes…
Healthy skin

Fungal Skin Microbiota is Discovered in Healthy Subjects

Posted on by skin_challenges
News Release, Skin Aging & Challenges – June 29, 2022 Beneficial microorganisms on the skin contribute to the first line of defense against attacking pathogens. However, instability of the skin microbiota is associated with skin diseases. Hence, temporal analyses are crucial because they serve as a baseline to understand the development of dysbiosis in disease. A recent…