Unlocking the Potential of Hydrogen Sulfide as a Healthy Ageing Therapeutic When Specifically Targeted Within Cells

Unlocking the Potential of Hydrogen Sulfide as a Healthy Ageing Therapeutic When Specifically Targeted Within Cells

Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated. A study from the University of Exeter, funded by the US Army and charity The United Mitochondrial Disease Foundation, found that targeting tiny amounts of H2S…
Posted on August 1, 2023
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The Mars-500 Mission: Does Space Travel Slow Down The Aging Process?

The Mars-500 Mission: Does Space Travel Slow Down The Aging Process?

Scientists have recently observed for the first time that, on an epigenetic level, astronauts age more slowly during long-term simulated space travel than they would have if their feet had been planted on Planet Earth. “Many of us assume that being exposed to radiation or other harm in space would be reflected by increased aging.…
Posted on July 26, 2023
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Bacteriophages and Microbiome in Dermatology: Potential Therapeutic Strategy

Bacteriophages and Microbiome in Dermatology: Potential Therapeutic Strategy

News release, Skin Challenges Task Force – July 24 Bacteriophages, also known as phages, are viruses that selectively target and infect bacteria. In addition to bacterial dysbiosis, dermatologic conditions such as acne, psoriasis, and atopic dermatitis are characterized by a relative reduction in the abundance of phages and the overgrowth of the corresponding bacteria. Phages…
Posted on July 24, 2023
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Pregnancy and Fetal Cells: New Actors in Wound Healing

Pregnancy and Fetal Cells: New Actors in Wound Healing

Wound healing is a complex biological process that involves various tissue structures and cells, both local and distant. One significant factor in this process is the presence of fetal microchimeric cells (FMCs) that enter the maternal circulation during pregnancy. These cells not only engraft into different organs but also nest in the maternal bone marrow…
Posted on July 12, 2023
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Hallmarks of Aging: An Expanding Universe

Hallmarks of Aging: An Expanding Universe

In their review published in Cell Press Journal, López-Otín et al. stated that aging is driven by hallmarks fulfilling the following three premises: (1) their age-associated manifestation, (2) the acceleration of aging by experimentally accentuating them, and (3) the opportunity to decelerate, stop, or reverse aging by therapeutic interventions on them. They proposed the following…
Posted on July 7, 2023
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Accelerated Wound Healing: Breakthrough Treatments

Accelerated Wound Healing: Breakthrough Treatments

Patients who undergo skin injuries endure hospital stays, infection and/or succumb to death; therefore, advances in wound healing aim to improve clinical practices underlying macroscale healing to effectively intervene in microscale pathophysiology. As a result, strategies that optimize wound healing have motivated the design of new therapeutic products. In a new report in Science Advances, Benjamin…
Posted on July 6, 2023
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The IL-17 protein plays a key role in skin ageing

The IL-17 protein plays a key role in skin ageing

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin ageing. The study, which was led by Dr. Guiomar Solanas, Dr. Salvador Aznar Benitah, both at IRB Barcelona, and Dr. Holger Heyn, at…
Posted on July 6, 2023
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Artificial Skin: Sensing Touch and Proximity that Exceeds Natural Skin

Artificial Skin: Sensing Touch and Proximity that Exceeds Natural Skin

Credit: The KonG/Adobe Stock As lovers might vouch, complex nuances of touch, including nearness sans physical contact and gradations of tactile pressure, convey a rich sensory experience and multi-dimensional cognitive pursuits. Intelligent interactions between biological entities or machines and organisms require artificial skins that can perceive fluctuations of intensity and pre-contact proximity. Until now, advances…
Posted on July 6, 2023
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Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging

Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging

The analysis of the role of the mitochondria in oxidative damage and skin aging has been a significant aspect of dermatological research. Mitochondria generate most reactive oxygen species (ROS) which, in excess, are cytotoxic and DNA-damaging and promote (photo-)aging. However, ROS also possesses key physiological and regulatory functions and mitochondrial dysfunction is prominent in several…
Posted on June 16, 2023
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