The IL-17 protein plays a key role in skin ageing

The IL-17 protein plays a key role in skin ageing

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin ageing. The study, which was led by Dr. Guiomar Solanas, Dr. Salvador Aznar Benitah, both at IRB Barcelona, and Dr. Holger Heyn, at…
Posted on July 6, 2023
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Artificial Skin: Sensing Touch and Proximity that Exceeds Natural Skin

Artificial Skin: Sensing Touch and Proximity that Exceeds Natural Skin

Credit: The KonG/Adobe Stock As lovers might vouch, complex nuances of touch, including nearness sans physical contact and gradations of tactile pressure, convey a rich sensory experience and multi-dimensional cognitive pursuits. Intelligent interactions between biological entities or machines and organisms require artificial skins that can perceive fluctuations of intensity and pre-contact proximity. Until now, advances…
Posted on July 6, 2023
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Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging

Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging

The analysis of the role of the mitochondria in oxidative damage and skin aging has been a significant aspect of dermatological research. Mitochondria generate most reactive oxygen species (ROS) which, in excess, are cytotoxic and DNA-damaging and promote (photo-)aging. However, ROS also possesses key physiological and regulatory functions and mitochondrial dysfunction is prominent in several…
Posted on June 16, 2023
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A Chronic Wound Model to Investigate Skin Cellular Senescence

A Chronic Wound Model to Investigate Skin Cellular Senescence

Wound healing is an essential physiological process for restoring normal skin structure and function post-injury. The role of cellular senescence, an essentially irreversible cell cycle state in response to damaging stimuli, has emerged as a critical mechanism in wound remodeling. Transiently-induced senescence during tissue remodeling has been shown to be beneficial in the acute wound…
Posted on May 15, 2023
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Evolution of the Facial Skin Microbiome During Puberty in Normal and Acne Skin

Evolution of the Facial Skin Microbiome During Puberty in Normal and Acne Skin

The composition of the skin microbiome varies from infancy to adulthood and becomes most stable in adulthood. Adult acne patients harbour an ‘acne microbiome’ dominated by specific strains of Cutibacterium acnes. However, the precise timing of skin microbiome evolution, the development of the acne microbiome, and the shift to virulent C. acnes strain composition during puberty is unknown. Schneider…
Posted on May 4, 2023
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Researchers use skin-colonizing bacteria to create a topical cancer therapy in mice

Researchers use skin-colonizing bacteria to create a topical cancer therapy in mice

In a study led by Stanford Medicine, researchers harnessed the skin’s immune response to bacteria to create an immunotherapy — delivered by swab — that treats aggressive tumors in mice. While studying a type of bacteria that lives on the healthy skin of every human being, researchers from Stanford Medicine and a colleague may have stumbled on…
Posted on April 19, 2023
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A Novel Hybrid Artificial Neural Network Technique for the Early Skin Cancer Diagnosis

A Novel Hybrid Artificial Neural Network Technique for the Early Skin Cancer Diagnosis

Tajjour et al. used an innovative hybrid machine learning-technique for the early skin cancer diagnosis fusing Convolutional Neural Network and Multilayer Perceptron to analyze images and information related to the skin cancer. This information is extracted manually after applying different color space conversions on the original images for better screening of the lesions. The proposed…
Posted on March 16, 2023
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Can algae enhance skin regeneration and wound healing?

Can algae enhance skin regeneration and wound healing?

Schematic of EMVEG encapsulating protein and lipid layer fragments and its confocal microscopy images of β-glucan and lipids labeled aniline blue (blue colored) and Texas red-DHPE (red colored), respectively A product of a freshwater single-celled green algae called Euglena gracilis may enhance skin regeneration to speed up wound healing, according to new research published in Advanced…
Posted on January 30, 2023
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Scientists develop novel mRNA delivery method using extracellular vesicles

Scientists develop novel mRNA delivery method using extracellular vesicles

Representative Masson trichrome collagen staining of the epidermis, dermis and subcutis for all mouse groups.  A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs). The new technique has the potential to overcome many of the delivery hurdles faced…
Posted on January 27, 2023
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