Author: skin_challenges

Revealing Fundamental Molecular Mechanisms of Aging and Lifespan Extension

Revealing Fundamental Molecular Mechanisms of Aging and Lifespan Extension

Posted on by skin_challenges
Despite centuries of medical research, pivotal questions about aging persist. A recent study by German scientists, published in Nature, suggests breakthrough insights into these questions. Researchers from the University of Cologne and Max Plank Institute for Biology of Aging, revealed an age-related acceleration in gene transcription coupled with reduced precision and increased errors. They reported…
Posted on August 29, 2023
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Sun Exposure Impact on Skin Microbiota Composition in Holidaymakers

Sun Exposure Impact on Skin Microbiota Composition in Holidaymakers

Posted on by skin_challenges
The skin microbiota plays a crucial role in maintaining epidermal homeostasis. Ultraviolet radiation (UVR) and other environmental challenges can impact the skin microbiota through direct and indirect mechanisms. In their study, Abigail K. Langton from the University of Manchester and her team, aimed to investigate the effects of sun exposure on the skin microbiota and…
Posted on August 18, 2023
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Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis

Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis

Posted on by skin_challenges
Previously either regarded as insignificant or feared as potential sources of infection, the bacteria living on our skin are increasingly recognized for their role in benefitting human health. Skin commensals modulate mucosal immune defenses and directly interfere with pathogens; however, their contribution to the skin’s physical integrity is less understood. In their study, published in…
Posted on August 11, 2023
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Unlocking the Potential of Hydrogen Sulfide as a Healthy Ageing Therapeutic When Specifically Targeted Within Cells

Unlocking the Potential of Hydrogen Sulfide as a Healthy Ageing Therapeutic When Specifically Targeted Within Cells

Posted on by skin_challenges
Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated. A study from the University of Exeter, funded by the US Army and charity The United Mitochondrial Disease Foundation, found that targeting tiny amounts of H2S…
Posted on August 1, 2023
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The Mars-500 Mission: Does Space Travel Slow Down The Aging Process?

The Mars-500 Mission: Does Space Travel Slow Down The Aging Process?

Posted on by skin_challenges
Scientists have recently observed for the first time that, on an epigenetic level, astronauts age more slowly during long-term simulated space travel than they would have if their feet had been planted on Planet Earth. “Many of us assume that being exposed to radiation or other harm in space would be reflected by increased aging.…
Posted on July 26, 2023
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Bacteriophages and Microbiome in Dermatology: Potential Therapeutic Strategy

Bacteriophages and Microbiome in Dermatology: Potential Therapeutic Strategy

Posted on by skin_challenges
News release, Skin Challenges Task Force – July 24 Bacteriophages, also known as phages, are viruses that selectively target and infect bacteria. In addition to bacterial dysbiosis, dermatologic conditions such as acne, psoriasis, and atopic dermatitis are characterized by a relative reduction in the abundance of phages and the overgrowth of the corresponding bacteria. Phages…
Posted on July 24, 2023
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Benefits of the Skin Challenges Task Force Group

Posted on by skin_challenges
The Skin Challenges Task Force Group brings together professionals from diverse fields such as dermatology, science, bioinformatics, electronics, and biosensors. The objective is to form a cohesive and multidisciplinary team capable of pushing the boundaries of research and innovation in skin ageing. Here are some steps you can consider to form and leverage a Task…
Posted on July 13, 2023
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Pregnancy and Fetal Cells: New Actors in Wound Healing

Pregnancy and Fetal Cells: New Actors in Wound Healing

Posted on by skin_challenges
Wound healing is a complex biological process that involves various tissue structures and cells, both local and distant. One significant factor in this process is the presence of fetal microchimeric cells (FMCs) that enter the maternal circulation during pregnancy. These cells not only engraft into different organs but also nest in the maternal bone marrow…
Posted on July 12, 2023
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Hallmarks of Aging: An Expanding Universe

Hallmarks of Aging: An Expanding Universe

Posted on by skin_challenges
In their review published in Cell Press Journal, López-Otín et al. stated that aging is driven by hallmarks fulfilling the following three premises: (1) their age-associated manifestation, (2) the acceleration of aging by experimentally accentuating them, and (3) the opportunity to decelerate, stop, or reverse aging by therapeutic interventions on them. They proposed the following…
Posted on July 7, 2023
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