Author: skin_challenges

Hallmarks of Aging: An Expanding Universe

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In their review published in Cell Press Journal, López-Otín et al. stated that aging is driven by hallmarks fulfilling the following three premises: (1) their age-associated manifestation, (2) the acceleration of aging by experimentally accentuating them, and (3) the opportunity to decelerate, stop, or reverse aging by therapeutic interventions on them. They proposed the following…

Artificial Intelligence and Skin Aging

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Skin Challenges Task Force Group will be launching a call for projects on the topic : “Artificial Intelligence & Skin Aging”. How is AI used in the skin aging? How AI will revolutionize personalized skincare, improve treatment outcomes, and contribute to our understanding of the complex processes underlying skin aging. Artificial intelligence (AI) has shown…

Skin Homeostasis in the context of Space Tourism : Towards the development of specialized skincare protocols and interventions for space travelers

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Skin Challenges Task Force Group will be launching a call for projects on the topic : “Skin Homeostasis & Space Tourism”. What is the concept of Skin Homeostasis in the context of Space Tourism? Space tourism, the concept of offering commercial trips to space for recreational purposes, poses unique challenges for human physiology, including skin…

Humanoid Robotics and Electronic Skin

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Skin Challenges Task Force Group will be launching a call for projects on the topic “Humanoid Robotics and Electronic Skin”. What do we mean by Humanoid Robotics and Electronic Skin? Humanoid robotics and electronic skin are interconnected fields that work together to create robots that have a more human-like appearance, movement capabilities, and sensory perception.…

Accelerated Wound Healing: Breakthrough Treatments

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Patients who undergo skin injuries endure hospital stays, infection and/or succumb to death; therefore, advances in wound healing aim to improve clinical practices underlying macroscale healing to effectively intervene in microscale pathophysiology. As a result, strategies that optimize wound healing have motivated the design of new therapeutic products. In a new report in Science Advances, Benjamin…

Artificial Skin: Sensing Touch and Proximity that Exceeds Natural Skin

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Credit: The KonG/Adobe Stock As lovers might vouch, complex nuances of touch, including nearness sans physical contact and gradations of tactile pressure, convey a rich sensory experience and multi-dimensional cognitive pursuits. Intelligent interactions between biological entities or machines and organisms require artificial skins that can perceive fluctuations of intensity and pre-contact proximity. Until now, advances…

Targeting mitochondria in dermatological therapy: beyond oxidative damage and skin aging

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The analysis of the role of the mitochondria in oxidative damage and skin aging has been a significant aspect of dermatological research. Mitochondria generate most reactive oxygen species (ROS) which, in excess, are cytotoxic and DNA-damaging and promote (photo-)aging. However, ROS also possesses key physiological and regulatory functions and mitochondrial dysfunction is prominent in several…

A Chronic Wound Model to Investigate Skin Cellular Senescence

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Wound healing is an essential physiological process for restoring normal skin structure and function post-injury. The role of cellular senescence, an essentially irreversible cell cycle state in response to damaging stimuli, has emerged as a critical mechanism in wound remodeling. Transiently-induced senescence during tissue remodeling has been shown to be beneficial in the acute wound…