Author: skin_challenges

Decoding Skin Aging: A miRNA-Based Epigenetic Clock for Precision Dermatology

Decoding Skin Aging: A miRNA-Based Epigenetic Clock for Precision Dermatology

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Is Your Skin Aging Faster Than You Think? The Science Behind Epigenetic Clocks. Discover how cutting-edge research on miRNA and epigenetics is reshaping the way we understand and measure skin aging. Breakthrough in Skin Aging Research  Researchers have identified a novel epigenetic molecular clock based on miRNA expression profiles that accurately predicts biological skin age.…
Posted on February 13, 2025
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Keynote Speaker 2025: Prof. Vladimir A. Botchkarev

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It is a great pleasure to welcome Professor Vladimir A. Botchkarev, Professor of Dermatology at the Boston University School of Medicine, USA, as a keynote speaker at Skin Ageing & Challenges 2025.  Topic: Epigenetic Regulation of Skin Ageing-Associated Genes in Short-Lived and Long-Lived Mammals.   About Prof. Botchkarev Currently a Professor of Dermatology and Co-Director…
Posted on January 30, 2025
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Ketone Bodies: A Promising Strategy for Enhancing Protein Quality Control in Brain Aging and Neurodegenerative Diseases

Ketone Bodies: A Promising Strategy for Enhancing Protein Quality Control in Brain Aging and Neurodegenerative Diseases

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A recent study published in Cell Chemical Biology by researchers at the Buck Institute for Research on Aging has uncovered significant roles of ketone bodies beyond energy production, particularly in brain function related to aging and Alzheimer’s disease.   Key findings include:   Direct Interaction with Misfolded Proteins: The ketone body β-hydroxybutyrate interacts directly with…
Posted on January 9, 2025
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Key Mechanisms Behind Age-Related Decline in Muscle Repair

Key Mechanisms Behind Age-Related Decline in Muscle Repair

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A recent study, led by Dr. Albert Hsiao and his team from Stanford University, highlighted three major findings that uncover the underlying causes of age-related muscle repair decline:   1.Discoordination in Muscle Repair: •Aging disrupts the timing of immune cell activity required for muscle repair. In younger muscles, immune cells, such as macrophages, arrive at…
Posted on January 9, 2025
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Are ‘Zombie Cells’ in Your Skin Accelerating Brain Aging?

Are ‘Zombie Cells’ in Your Skin Accelerating Brain Aging?

Posted on by skin_challenges
Mayo Clinic researchers have discovered that senescent cells—non-dividing “zombie” cells—accumulate in the skin as people age and may contribute to aging in other parts of the body, including the brain. Published in Aging Cell, their study shows that transplanting senescent skin cells into a preclinical model not only spreads senescence to other tissues but also…
Posted on December 3, 2024
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Who Attended Skin Ageing & Challenges 2024?

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Among Industrials CosmeticOBS (Partner) OPTIMEALTH® Amoeba Apivita S.A. Arterra Bioscience S.p.A. Antoniol Puig S.A. AV Laboratories LLC Beiersdorf AG Essity Hygiene and Health AB Evonik Chanel Parfums Beauté Contipro Coty Caudalie Chemisches Laboratorium Dr. Kurt Richter Givaudan Active Beauty Dermostica Institute Dr Irena Eris SA Evonik Givaudan Active Beauty Groupe NAOS HysensBio Herbalife IL Cosmetics…
Posted on November 7, 2024
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Skin Ageing & Challenges 2024 Replay & Abstracts Book

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If you were not able to attend the congress online or in-person, the abstracts book and recordings of all presentations of Skin Ageing & Challenges 2024 are now available for purchase.   Skin Ageing & Challenges 2024 Congress – Replay Access You can catch up on all the details of the 15th International Conference of…
Posted on November 7, 2024
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SENISCA’s Small Molecule Reduces Senescence in Aged Cells – Best Short Oral at Skin Challenges 2024

SENISCA’s Small Molecule Reduces Senescence in Aged Cells – Best Short Oral at Skin Challenges 2024

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Congratulations to Adam Clauss from SENISCA Ltd, UK, for winning the Best Short Oral Presentation Award at Skin Ageing & Challenges 2024! His groundbreaking research, “A Groundbreaking Intervention Effectively Reduces Senescence in Old Primary Cells by Targeting a New Hallmark of Ageing,” highlights the potential of small molecule modulators of splicing factor expression to reverse…
Posted on November 6, 2024
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“Inhibition of Thioredoxin Reductase 1 Activates NRF2 Pathway” Wins Skin Challenges 2024 Best Poster Award (2)

“Inhibition of Thioredoxin Reductase 1 Activates NRF2 Pathway” Wins Skin Challenges 2024 Best Poster Award (2)

Posted on by skin_challenges
Congratulations to Jakub Pawlikowski from Silesian University of Technology, Poland, on winning the Best Poster Presentation Award (2) at Skin Ageing & Challenges 2024! His study, “Suppression of Thioredoxin Reductase 1 in Keratinocyte Cell Line as a Key Regulator of the NRF2 Pathway,” reveals how inhibiting TXNRD1 disrupts redox balance, activating NRF2 to protect skin…
Posted on November 6, 2024
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