Dr. Ardeshir Bayat

Novel state of the art topicals & regimens show statistically significant improvement in cutaneous photoaging

During the Skin Challenges 2020 congress, which will be held on November 5-6, 2020 in Porto, Portugal, Dr. Ardeshir Bayat, from the University of Manchester in England, will give a presentation entitled “Novel state of the art topicals & regimens show statistically significant improvement in cutaneous photoaging“.

Dr. Ardeshir Bayat trained as a clinician-scientist BSc (Hons) MB BS MRCS PhD. His research work is focused on the subject of skin repair, rejuvenation and regeneration. His laboratory is based at the University of Manchester in England as well as the University of Cape Town in South Africa.

Summary of talk: Novel rotational combination regime with unique topical combinations show statistically significant improvement of facial skin photoaging as demonstrated by in vitro, ex vivo, and in vivo double year-long, split-face, evaluator-blinded IRB-approved clinical trials. In addition, clinical efficacy and mechanism of action of novel non-natural, non-proteogenic amino acids in skin anti-aging will be presented.

Skin Ageing & Challenges 2020
November 5-6, 2020 – Porto, Portugal
www.skin-challenges.com

Prof. Shigefumi Okamoto

Distinct skin microbiome and skin physiological functions between bedridden older patients and healthy people: A single-center study in Japan

Prof. Shigefumi Okamoto from Kanazawa University Institute of Medical, Pharmaceutical, and Health Sciences, Japan will join the Skin Challenges 2020 Virtual Congress and present his research on Distinct skin microbiome and skin physiological functions between bedridden older patients and healthy people: A single-center study in Japan.

With the increase in the older populations, the number of bedridden older patients is becoming a matter of concern. Skin microbiome and skin physiological functions are known to change according to lifestyle and community; however, such changes in case of movement- and cleaning-restricted bedridden older patients have not yet been revealed. To address this issue, we analyzed skin microbiome and skin physiological functions, including pH, hydration, sebum level, and transepidermal water loss (TEWL), of bedridden older patients, compared with those of ambulatory older For this analysis, we enrolled 19 healthy young and 18 ambulatory older individuals from the community and 31 bedridden older patients from a single, long-term care hospital in Japan. The area of interest was set to the sacral (lower back ) skin, where pressure injuries (PIs) and subsequent infection frequently occurs in bedridden older patients. We observed a higher number of gut-related bacteria, fewer commensals, higher skin pH, and lower TEWL on the sacral skin of bedridden older patients than on that of young or ambulatory older individuals. In addition, we observed that 4 of the 31 bedridden older patients developed PIs during the research period; a higher abundance of pathogenic skin bacteria was also observed inside the PI wounds. These findings imply distinct skin microbiome and skin physiological functions in bedridden older patients in comparison with healthy individuals and may suggest the need for more stringent cleaning of the skin of bedridden older patients in light of the closeness of skin and wound microbiome.

Skin Ageing & Challenges  2020
November 5-6, 2020
www.skin-challenges.com

Introduction on the role of iron and hepcidin in the process of cells and wound healing

Dr. Charareh Pourzand from University of Bath, United Kingdom, will join the Skin Ageing & Challenges 2020 Congress which will be held on November 5-6, 2020 in Porto, Portugal and will give a presentation entitled “Introduction on the role of iron and hepcidin in the process of cells and wound healing“.

Dr. Pourzand highlights: Here I will first introduce the knowledge that currently links iron homeostasis to skin cells’ function and wound healing process. I will then  talk about how the process of ageing and photo-ageing can disturb the iron homeostasis. I will also provide a brief summary of the relationship that exists between wound healing process in the skin and iron deficiency. I will finish my talk with some of the innovative strategies that we have recently developed  to counteract the iron-mediated damage against aged /photoaged skin.

Skin Ageing & Challenges 2020
November 5-6, 2020 – Porto, Portugal
www.skin-challenges.com

The imaging technique to evaluate oxidative stress in the human skin

Prof. Masaki Kobayashi, from Tohoku Institute of Technology, Japan, will join the Skin Challenges 2020 congress and will give a presentation entitled “The imaging technique to evaluate oxidative stress in the human skin“.

Summary of talk: Imaging of ultra-weak photon emission (UPE or biophoton) from skin surface has the potential to non-invasively visualize the state of oxidative stress in the skin. Technologies for the imaging and spectral analysis of UPE will be presented with characterizing the spontaneous and UV-induced UPE phenomena of human skin. The dermatological application of UPE including the mechanisms will be discussed.

Skin Ageing & Challenges 2020
November 5-6, 2020 – Virtual Congress
www.skin-challenges.com

Granzymes: Strategic Role in Skin Aging and Inflammatory Skin Conditions

The scientific committee of the Skin Challenges 2020 Congress is honored to announce the participation of  Prof. David Granville from the University of British Columbia, Canada. Prof. David Granville will give a presentation entitled “Granzymes: Strategic Role in Skin Aging and Inflammatory Skin Conditions“.

Summary of talk  : Granzymes are a family of 5 serine proteases (humans) that were once thought to function exclusively in lymphocyte-mediated cell death. However, in recent years, it has become clear that in the context of disease, these proteases can exert non-cytotoxic roles pertaining to inflammation, extracellular matrix degradation, activation of cell surface receptors and disruption of epithelial barrier function. Preclinical studies using a combination of genetic knockout approaches and novel topical granzyme B inhibitors have demonstrated an important role for granzyme B in photoaging and other inflammatory skin pathologies. My talk will focus in on recent findings pertaining to granzymes, epithelial barrier disruption and dermatitis.`

Skin Ageing & Challenges 2020
November 5-6, 2020 – Virtual Congress
www.skin-challenges.com

 

Artificial Intelligence & Future of Skin Science

The scientific committee is pleased to announce during Skin Ageing & Challenges 2020, a session dedicated to Artificial Intelligence & Skincare.

The aim of this session is to present the last advances and innovations in the field of Artificial Intelligence (AI) applied to Skincare, and to connect all the key actors involved in skin assessment and analysis: clinician, dermatologist, academic, start-up, industrial, mathematician, computer scientists, and bioinformatician, in order to initiate the discussions on the development and applications of novel AI technologies to skincare.

All scientists and industrials are invited to present their last innovations.

Please don’t hesitate to contact us with any complementary information.

To submit an abstract for the session, please find all modalities here.

New insights into skin ageing

The scientific committee is pleased to announce that Prof. Christopher Griffiths, from University of Manchester, United Kingdom, will give a talk on the New insights into skin ageing“, during Porto Skin Ageing & Challenges Congress 2020, which will be held in Porto, on November 5-6, 2020.

Prof. Griffiths will highlight following topics during his talk:

– Skin ageing is recognized as a confluence of genetic predisposition and environmental influences such as sunlight, diet etc.

– Photoageing of the skin  – the combination of chronic exposure to sunlight and intrinsic ageing – manifests as either atrophic or hypertrophic with distinct clinical and histological characteristics.

– Future work on skin ageing will focus much more on lifestyle to enable a prolongation of healthspan and on a personalized approach to management.

For more information: www.skin-challenges.com

 

Call for Abstracts & Key dates

The Scientific Committee invites all scientists, academics, and industrials to present their researches in recent innovations, biotechnology products, and devices during the two days of the conference.

Deadline for Oral Presentation Submission: October 5, 2020
Deadline for Poster Presentation Submission: October 12, 2020

 
Dr. Thomas Haarmann-Stemmann

Interaction of different UV wavelengths present in natural sunlight

Dr. Thomas Haarmann-Stemmann from Leibniz Research Institute for Environmental Medicine, Germany will present his study on “Interaction of different UV wavelengths present in natural sunlight” during  Porto Skin Ageing & Challenges Congress 2020 which will be held in Porto, on November 5-6, 2020.

For more information: www.skin-challenges.com

 

Skin aging in Indians living in highly polluted areas

Dr. Tamara Schikowsk

Dr. Tamara Schikowsk from Leibniz Research Institute for Environmental Medicine, Germany will give a presentation entitled “Skin aging in Indians living in highly polluted areas” during  Porto Skin Ageing & Challenges Congress 2020 which will be held in Porto, on November 5-6, 2020.

For more information: www.skin-challenges.com