In-cytoplasm Mitochondrial Transplantation for Stem Cells Engineering & Tissue Regeneration

In-cytoplasm Mitochondrial Transplantation for Stem Cells Engineering & Tissue Regeneration

Representative images of the wound area (left) and the corresponding fractions of wounds healed (right) by different treatments. News Release, Skin Aging & Challenges – August 31, 2022 Stem cell therapies are unsatisfactory due to poor cell survival and engraftment. Stem cells used for therapy must be properly “tuned” for a harsh in vivo environment.…
Posted on August 31, 2022
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Topical Platelet Exosomes: New Strategy for Skin Rejuvenation

Topical Platelet Exosomes: New Strategy for Skin Rejuvenation

News release, Skin Ageing & Challenges – 23 June 2022 Exosomes are regenerative mediators for skin rejuvenation. In the context of aesthetic medicine, platelets are an ideal source for exosomal isolation given their role in skin healing. Human platelet extract (HPE) is an allogeneic exosome product derived from US-sourced, leukocyte-reduced apheresed platelets with consistent purity…
Posted on August 23, 2022
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Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Against Photoaging

Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Against Photoaging

News Release, Skin Aging & Challenges – August 8, 2022 Oxidative stress and mitochondrial dysfunction play a role in the process of skin photoaging via activation of matrix metalloproteases (MMPs) and the subsequent degradation of collagen. The activation of nuclear factor E2-related factor 2 (Nrf2), a transcription factor controlling antioxidant and cytoprotective defense systems, might…
Posted on August 8, 2022
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Skin Cells Made Up To 40 Years Younger with New “Rejuvenation” Technique

Skin Cells Made Up To 40 Years Younger with New “Rejuvenation” Technique

Aging is the gradual decline in cell and tissue function over time. It is characterized by various factors, including telomere attrition, genetic instability, and misfolded proteins. The progression of some age-related changes can be measured and used to predict age in humans. Induced pluripotent stem cell (iPSC) reprogramming is a process in which any cell can be converted into an…
Posted on July 21, 2022
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In-vivo Skin Cancer Diagnosis via Real-Time High-Resolution Millimeter-Wave Imaging

In-vivo Skin Cancer Diagnosis via Real-Time High-Resolution Millimeter-Wave Imaging

Schematic of the developed ultra-wideband millimeter-wave imaging system for real-time in-vivo skin cancer imaging. News Release, Skin Aging & Challenges – July 11, 2022 High-resolution millimeter-wave imaging (HR-MMWI), with its high discrimination contrast and sufficient penetration depth, can potentially provide affordable tissue diagnostic information noninvasively. Mirbeik et al. evaluated the application of a real-time system…
Posted on July 11, 2022
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Extracellular Vesicles: Potential Theranostic Platforms for Skin Diseases and Aging

Extracellular Vesicles: Potential Theranostic Platforms for Skin Diseases and Aging

Conceptual overview of EVs and their associated effects on skin News Release, Skin Aging & Challenges – July 8, 2022 Extracellular vesicles (EVs), naturally secreted by cells, act as mediators for communication between cells. They are transported to the recipient cells along with cargoes such as nucleic acids, proteins, and lipids that reflect the changes…
Posted on July 8, 2022
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Fungal Skin Microbiota is Discovered in Healthy Subjects

Fungal Skin Microbiota is Discovered in Healthy Subjects

News Release, Skin Aging & Challenges – June 29, 2022 Beneficial microorganisms on the skin contribute to the first line of defense against attacking pathogens. However, instability of the skin microbiota is associated with skin diseases. Hence, temporal analyses are crucial because they serve as a baseline to understand the development of dysbiosis in disease. A recent…
Posted on June 29, 2022
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Microelectronic Skins: A New Revolution?

Microelectronic Skins: A New Revolution?

Ulsan National Institute’s electronic skin News Release, Skin Aging & Challenges – June 29, 2022 Magnetic sensors are widely used in our daily life for assessing the position and orientation of objects. Recently, the magnetic sensing modality has been introduced to electronic skins (e-skins), enabling remote perception of moving objects. However, the integration density of…
Posted on June 29, 2022
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Flavonoids: Skin Senescence Prevention & Treatment

Flavonoids: Skin Senescence Prevention & Treatment

News release, Skin Ageing & Challenges – 21 June 2022 Skin aging is associated with the accumulation of senescent cells and is related to many pathological changes, including decreased protection against pathogens, increased susceptibility to irritation, delayed wound healing, and increased cancer susceptibility. Senescent cells secrete a specific set of pro-inflammatory mediators, referred to as…
Posted on June 21, 2022
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