Category: News & Media

Targeting ApoD with Antibody-Drug Conjugates: A New Era in Senolysis for Skin Rejuvenation

Targeting ApoD with Antibody-Drug Conjugates: A New Era in Senolysis for Skin Rejuvenation

Posted on by skin_challenges
A study published in the International Journal of Molecular Sciences has revealed a novel senolysis approach that specifically targets senescent cells in aging skin, paving the way for potential clinical applications in treating pathological skin aging and related diseases. As we age, senescent cells accumulate in our skin, causing age-related changes and a decline in…
Posted on March 5, 2024
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Ethical Landscape of Artificial Intelligence in Dermatology

Ethical Landscape of Artificial Intelligence in Dermatology

Posted on by skin_challenges
The field of dermatology is undergoing a transformative phase with the rapid integration of artificial intelligence (AI) technologies. From mobile applications designed for skin cancer detection to sophisticated language models like ChatGPT capable of addressing both generalist and specialist inquiries regarding skin diagnoses, AI is reshaping clinical practice. However, as these innovations proliferate, ethical considerations…
Posted on February 27, 2024
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Turning back the clock on photoaging skin

Turning back the clock on photoaging skin

Posted on by skin_challenges
Chronic exposure of human skin to ultraviolet light causes premature aging, or photoaging. As the skin undergoes photoaging, type I collagen bundles, which are found in the dermis beneath the top layer of the skin and provide strength and support to skin, become fragmented. This leads to wrinkles, fragility and loss of support and elasticity.  …
Posted on February 22, 2024
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Natural Products as Immunomodulators in skin and Skincare: Potential, Challenges, and Future Directions

Natural Products as Immunomodulators in skin and Skincare: Potential, Challenges, and Future Directions

Posted on by skin_challenges
This excellent review published by A. Fernandes and her team from Universidade Católica Portuguesa in Phytomedicine Journal (Elsevier) presents a comprehensive review of the potential of natural products in treating various skin conditions through immunomodulation. It highlights the growing interest in natural molecules, such as polyphenols, polysaccharides, fatty acids, peptides, and probiotics, for their roles in…
Posted on February 19, 2024
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Reversing Skin Aging: The Power of Senolytics Revealed

Reversing Skin Aging: The Power of Senolytics Revealed

Posted on by skin_challenges
In a study published in September 2023 by Karin Scharffetter-Kochanek and team, the focus is on how our skin and organs age, mainly due to a process called cellular senescence, which also links to various diseases that come with getting older. The research investigates some cutting-edge treatments, including senolytics, senomorphics, and cell-based therapies, that aim…
Posted on February 12, 2024
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L-Lactate: A Key Player in Skin Aging and Health

L-Lactate: A Key Player in Skin Aging and Health

Posted on by skin_challenges
Skin Ageing & Challenges, which will be held on November 7-8 2024 at Corinthia Palace Malta, started the preparation of its annual conference, with a focus on innovative and new research. In an innovative study recently published in Biogerontology Journal (Springer), researchers explore the intricate world of cellular metabolism and its profound implications for skin…
Posted on February 8, 2024
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High-Frequency Ultrasound in Anti-Aging Skin Therapy Monitoring

High-Frequency Ultrasound in Anti-Aging Skin Therapy Monitoring

Posted on by skin_challenges
Left: facial model with superimposed image acquisition areas. Right: exemplary HFUS skin areas with segmented ROI for parameters estimation. A recent research by Joanna Czajkowska and her team at the Silesian University of Technology, showcased the transformative potential of high-frequency ultrasound (HFUS) in anti-aging skin therapy assessment. The study, a first in its field, delves…
Posted on February 2, 2024
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Engineered Skin Bacterium Holds Promise for Revolutionary Acne Treatment

Engineered Skin Bacterium Holds Promise for Revolutionary Acne Treatment

Posted on by skin_challenges
International research led by the Translational Synthetic Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University has succeeded in efficiently engineering Cutibacterium acnes, a type of skin bacterium, to produce and secrete a therapeutic molecule suitable for treating acne symptoms. The engineered bacterium has been validated in skin cell…
Posted on January 12, 2024
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Biomimetic E-Skin Sparks Neuronal Activity for Enhanced Human-Machine Interaction

Biomimetic E-Skin Sparks Neuronal Activity for Enhanced Human-Machine Interaction

Posted on by skin_challenges
Exciting developments in prosthetic electronic skin (e-skin) have emerged from a recent paper by Wang et al. published in the Science journal. The researchers, from Stanford University, have engineered a soft e-skin that replicates both the mechanical properties and sensory feedback of natural skin, presenting promising possibilities for next-generation robotic and medical devices. Key Features…
Posted on January 2, 2024
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BJ-5ta Exosomes Clarified: A Breakthrough Defense Against UVB-Induced Skin Aging

BJ-5ta Exosomes Clarified: A Breakthrough Defense Against UVB-Induced Skin Aging

Posted on by skin_challenges
A newly published paper by researchers from the Republic of Korea reveals the promising potential of BJ-5ta Exosomes in combating the adverse effects of UVB radiation on the skin. Exosomes, tiny vesicles with transformative properties, have long been recognized as innovative treatment options for various skin conditions, including aging, atopic dermatitis, and wounds. However, the…
Posted on December 19, 2023
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