Category: News & Media

Reversing Skin Aging: The Power of Senolytics Revealed

Posted on by skin_challenges
In a study published in September 2023 by Karin Scharffetter-Kochanek and team, the focus is on how our skin and organs age, mainly due to a process called cellular senescence, which also links to various diseases that come with getting older. The research investigates some cutting-edge treatments, including senolytics, senomorphics, and cell-based therapies, that aim…
Skin Ageing & Challenges - Skin Health

L-Lactate: A Key Player in Skin Aging and Health

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Skin Ageing & Challenges, which will be held on November 7-8 2024 at Corinthia Palace Malta, started the preparation of its annual conference, with a focus on innovative and new research. In an innovative study recently published in Biogerontology Journal (Springer), researchers explore the intricate world of cellular metabolism and its profound implications for skin…
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High-Frequency Ultrasound in Anti-Aging Skin Therapy Monitoring

Posted on by skin_challenges
Left: facial model with superimposed image acquisition areas. Right: exemplary HFUS skin areas with segmented ROI for parameters estimation. A recent research by Joanna Czajkowska and her team at the Silesian University of Technology, showcased the transformative potential of high-frequency ultrasound (HFUS) in anti-aging skin therapy assessment. The study, a first in its field, delves…

Engineered Skin Bacterium Holds Promise for Revolutionary Acne Treatment

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International research led by the Translational Synthetic Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University has succeeded in efficiently engineering Cutibacterium acnes, a type of skin bacterium, to produce and secrete a therapeutic molecule suitable for treating acne symptoms. The engineered bacterium has been validated in skin cell…

Biomimetic E-Skin Sparks Neuronal Activity for Enhanced Human-Machine Interaction

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Exciting developments in prosthetic electronic skin (e-skin) have emerged from a recent paper by Wang et al. published in the Science journal. The researchers, from Stanford University, have engineered a soft e-skin that replicates both the mechanical properties and sensory feedback of natural skin, presenting promising possibilities for next-generation robotic and medical devices. Key Features…

BJ-5ta Exosomes Clarified: A Breakthrough Defense Against UVB-Induced Skin Aging

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A newly published paper by researchers from the Republic of Korea reveals the promising potential of BJ-5ta Exosomes in combating the adverse effects of UVB radiation on the skin. Exosomes, tiny vesicles with transformative properties, have long been recognized as innovative treatment options for various skin conditions, including aging, atopic dermatitis, and wounds. However, the…

Revealing Fundamental Molecular Mechanisms of Aging and Lifespan Extension

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Despite centuries of medical research, pivotal questions about aging persist. A recent study by German scientists, published in Nature, suggests breakthrough insights into these questions. Researchers from the University of Cologne and Max Plank Institute for Biology of Aging, revealed an age-related acceleration in gene transcription coupled with reduced precision and increased errors. They reported…

Sun Exposure Impact on Skin Microbiota Composition in Holidaymakers

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The skin microbiota plays a crucial role in maintaining epidermal homeostasis. Ultraviolet radiation (UVR) and other environmental challenges can impact the skin microbiota through direct and indirect mechanisms. In their study, Abigail K. Langton from the University of Manchester and her team, aimed to investigate the effects of sun exposure on the skin microbiota and…

Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis

Posted on by skin_challenges
Previously either regarded as insignificant or feared as potential sources of infection, the bacteria living on our skin are increasingly recognized for their role in benefitting human health. Skin commensals modulate mucosal immune defenses and directly interfere with pathogens; however, their contribution to the skin’s physical integrity is less understood. In their study, published in…