Category: News & Media

Senescence in Ageing Skin: A New Focus on mTORC1 and the Lysosome

Senescence in Ageing Skin: A New Focus on mTORC1 and the Lysosome

Posted on by skin_challenges
Cellular senescence in the skin. Aging is characterized by the progressive decline of tissue function and regenerative capacity, influenced by both intrinsic factors (natural accumulation of damage) and extrinsic stressors such as ultraviolet (UV) exposure and oxidative stress. Cellular senescence—an irreversible exit from the cell cycle triggered by excessive damage—has been extensively linked to tissue…
Posted on February 18, 2025
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Decoding Skin Aging: A miRNA-Based Epigenetic Clock for Precision Dermatology

Decoding Skin Aging: A miRNA-Based Epigenetic Clock for Precision Dermatology

Posted on by skin_challenges
Is Your Skin Aging Faster Than You Think? The Science Behind Epigenetic Clocks. Discover how cutting-edge research on miRNA and epigenetics is reshaping the way we understand and measure skin aging. Breakthrough in Skin Aging Research  Researchers have identified a novel epigenetic molecular clock based on miRNA expression profiles that accurately predicts biological skin age.…
Posted on February 13, 2025
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Ketone Bodies: A Promising Strategy for Enhancing Protein Quality Control in Brain Aging and Neurodegenerative Diseases

Ketone Bodies: A Promising Strategy for Enhancing Protein Quality Control in Brain Aging and Neurodegenerative Diseases

Posted on by skin_challenges
A recent study published in Cell Chemical Biology by researchers at the Buck Institute for Research on Aging has uncovered significant roles of ketone bodies beyond energy production, particularly in brain function related to aging and Alzheimer’s disease.   Key findings include:   Direct Interaction with Misfolded Proteins: The ketone body β-hydroxybutyrate interacts directly with…
Posted on January 9, 2025
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Key Mechanisms Behind Age-Related Decline in Muscle Repair

Key Mechanisms Behind Age-Related Decline in Muscle Repair

Posted on by skin_challenges
A recent study, led by Dr. Albert Hsiao and his team from Stanford University, highlighted three major findings that uncover the underlying causes of age-related muscle repair decline:   1.Discoordination in Muscle Repair: •Aging disrupts the timing of immune cell activity required for muscle repair. In younger muscles, immune cells, such as macrophages, arrive at…
Posted on January 9, 2025
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Are ‘Zombie Cells’ in Your Skin Accelerating Brain Aging?

Are ‘Zombie Cells’ in Your Skin Accelerating Brain Aging?

Posted on by skin_challenges
Mayo Clinic researchers have discovered that senescent cells—non-dividing “zombie” cells—accumulate in the skin as people age and may contribute to aging in other parts of the body, including the brain. Published in Aging Cell, their study shows that transplanting senescent skin cells into a preclinical model not only spreads senescence to other tissues but also…
Posted on December 3, 2024
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Skin barrier protein also protects against inflammation

Skin barrier protein also protects against inflammation

Posted on by skin_challenges
@ Press Release from University of California – San Diego Researchers at University of California San Diego School of Medicine have identified a new mechanism underlying inflammatory skin diseases, such as psoriasis and seborrheic dermatitis. They found that a protein essential in forming the skin’s protective barrier (ZNF750) also plays a role in controlling inflammation…
Posted on October 10, 2024
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Key molecule in wound healing identified

Key molecule in wound healing identified

Posted on by skin_challenges
Photo & Press Release: Karolinska Institutet A new study by researchers from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has uncovered a crucial RNA molecule involved in skin wound healing. Published in Nature Communications, this discovery may open new avenues for treating difficult-to-heal wounds. The research highlights the molecular processes behind…
Posted on October 10, 2024
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Infrared Radiation: A Double-Edged Sword for Skin Health

Infrared Radiation: A Double-Edged Sword for Skin Health

Posted on by skin_challenges
Researchers from University of California Irvine, University of Oklahoma and Henry Ford Medical Center have highlighted the complex effects of infrared radiation (IR) on human skin. The study explores both the detrimental and beneficial impacts of IR, providing a comprehensive overview of the current understanding of how this type of radiation influences skin health. Infrared radiation,…
Posted on September 12, 2024
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Exploring New Mechanisms of Skin Aging: The Role of Mitophagy and Extracellular Vesicles

Exploring New Mechanisms of Skin Aging: The Role of Mitophagy and Extracellular Vesicles

Posted on by skin_challenges
A recent study by researchers from the University of Innsbruck, Austria, sheds new light on the mechanisms underlying skin aging, particularly in relation to mitochondrial quality control. Co-author Ines Martic will join the upcoming “Skin Ageing & Challenges” conference in November to present these innovative findings. The research addresses the two types of skin aging:…
Posted on September 4, 2024
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Next-Generation Artificial Skin: Advancing Tactile Sensation and Promoting Wound Healing

Next-Generation Artificial Skin: Advancing Tactile Sensation and Promoting Wound Healing

Posted on by skin_challenges
Overall schematic of the WTSA and converted tactile signal transfer process to stimulate the sciatic nerve. A new study published in Nature Communications has revealed an innovative advancement in skin regeneration and sensory restoration. Researchers have developed the Wireless Powered Tactile Sensory System Embedded Artificial Skin (WTSA), a novel technology designed to address severe skin…
Posted on August 23, 2024
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