Skin barrier protein also protects against inflammation

@ Press Release from University of California – San Diego Researchers at University of California San Diego School of Medicine have identified a new mechanism underlying inflammatory skin diseases, such as psoriasis and seborrheic dermatitis. They found that a protein essential in forming the skin’s protective barrier (ZNF750) also plays a role in controlling inflammation…
Photo & Press Release: Karolinska Institutet

Key molecule in wound healing identified

Photo & Press Release: Karolinska Institutet A new study by researchers from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has uncovered a crucial RNA molecule involved in skin wound healing. Published in Nature Communications, this discovery may open new avenues for treating difficult-to-heal wounds. The research highlights the molecular processes behind…

Infrared Radiation: A Double-Edged Sword for Skin Health

Researchers from University of California Irvine, University of Oklahoma and Henry Ford Medical Center have highlighted the complex effects of infrared radiation (IR) on human skin. The study explores both the detrimental and beneficial impacts of IR, providing a comprehensive overview of the current understanding of how this type of radiation influences skin health. Infrared radiation,…

Exploring New Mechanisms of Skin Aging: The Role of Mitophagy and Extracellular Vesicles

A recent study by researchers from the University of Innsbruck, Austria, sheds new light on the mechanisms underlying skin aging, particularly in relation to mitochondrial quality control. Co-author Ines Martic will join the upcoming “Skin Ageing & Challenges” conference in November to present these innovative findings. The research addresses the two types of skin aging:…

Next-Generation Artificial Skin: Advancing Tactile Sensation and Promoting Wound Healing

Overall schematic of the WTSA and converted tactile signal transfer process to stimulate the sciatic nerve. A new study published in Nature Communications has revealed an innovative advancement in skin regeneration and sensory restoration. Researchers have developed the Wireless Powered Tactile Sensory System Embedded Artificial Skin (WTSA), a novel technology designed to address severe skin…

Innovative Diagnostics: How Facial Temperature Could Transform Early Metabolic Disease Detection

Average facial temperatures of three aging-status groups among women 50-60 years old. Credit: Zhengqing Yu and Jing-Dong J Han. Dr. Jing-Jong Han will join Skin Ageing & Challenges 2024 this November to discuss her latest findings on the innovative thermal imaging techniques for detecting aging disorders with a focus on the “ThermaFace Method”. Join us…

Metformin-Engineered Extracellular Vesicles: Strategic Role in Aging Skin Repair

Schematic diagram shows the Met-EV–mediated biological performance. Met-EV could mediate the activation of mitophagy, rescue of mitochondria, and reprogramming of energy metabolism in fibroblasts.   Researchers from the Shanghai Jiao Tong University School of Medicine have discovered a novel approach to enhancing the repair of aging skin, a common issue marked by impaired wound healing…

Iron Metabolism in Skin: Implications for Skin Ageing and Health

Schematic depiction of the iron metabolism in the epidermis. The process of keratinocyte differentiation is represented by cells in the basal layer, the granular layer and the cornified layer. The distribution of iron-binding proteins and regulators of iron metabolism and transport is shown according to the evidence and hypotheses discussed in the main text. Alternative…

Cellular Senescence: Novel Interventions for Combating Skin Aging

Hallmarks of skin aging. An illustration of skin senescent cell accumulation and corresponding senescence-associated secretory phenotype (SASP) factor release in young versus old human skin models. Researchers from the Mayo Clinic, led by Dr. Saranya Wyles, have shed new light on the complex processes of skin aging, emphasizing the critical role of cellular senescence. As…