A new driver of inflammation in aging: Mitochondrial RNA leakage
A major new study authored by Stella Victorelli and Madeline Eppard and led by Joao Passos, of Mayo Clinic, uncovers a previously unknown mechanism driving chronic inflammation in aging. The research indicates that mitochondrial RNA (mtRNA) leaking into the cytosol of senescent cells acts as a key trigger for the senescence-associated secretory phenotype (SASP), a…
