Can Aging Skin Accelerate Brain and Body Decline?

Can Aging Skin Accelerate Brain and Body Decline?

Recent research suggests that skin aging is not merely a cosmetic concern but may actively contribute to systemic aging processes, including cognitive decline. This article explores the mechanisms by which skin senescence influences whole-body and brain aging and discusses potential interventions. Key Findings: Skin-Brain Aging Connection: Transplanting senescent cells into the skin of young mice…
Posted on May 6, 2025
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Neuro–immuno–endocrinology of the Skin: A Central Regulator of Environmental Homeostasis

Neuro–immuno–endocrinology of the Skin: A Central Regulator of Environmental Homeostasis

Prof. Andrzej T. Slominski et al. published an excellent paper titled “Neuro–immuno–endocrinology of the skin: how environment regulates body homeostasis” in Nature Reviews Endocrinology (2025). This review highlights the pivotal role of the skin as an integrative neuro–immuno–endocrine organ that not only serves as a protective barrier but also actively participates in systemic regulation. Key…
Posted on May 5, 2025
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Book Your Stay at The Westin Valencia for Skin Ageing & Challenges 2025

Book Your Stay at The Westin Valencia for Skin Ageing & Challenges 2025

Exclusive Accommodation for Conference Attendees Join us for the 16th International Conference on Skin Ageing & Challenges on November 11-12, 2025 at the prestigious The Westin Valencia in the heart of Valencia, Spain. Special Conference Rate Available Now! The Skin Ageing & Challenges committee has secured an exclusive reduced rate for all attendees: King Guest…
Posted on March 31, 2025
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What if we’ve been measuring the wrong microbes all along?

What if we’ve been measuring the wrong microbes all along?

For years, scientists have studied the skin microbiome by analyzing DNA found on the surface of our skin. But there’s a big problem: that DNA doesn’t just come from living bacteria—it also comes from dead ones, long gone but still leaving traces behind. A team of researchers decided to tackle this issue head-on. They used…
Posted on March 24, 2025
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The Role of the Microbiome in Aging-Related Diseases : The Targets

The Role of the Microbiome in Aging-Related Diseases : The Targets

Growth and aging are fundamental aspects of human, with aging characterized by a decline in physiological functions and increased susceptibility to diseases. Influenced by genetic, environmental, and lifestyle factors, aging is associated with various disorders, including cardiovascular, musculoskeletal, and neurological diseases, which contributed to 16.1 million deaths globally in 2019. Cellular senescence, triggered by stress-induced…
Posted on March 4, 2025
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Senolytic & Senomorphic Agents – Strategies and Impact on Rejuvenation

Why a session dedicated to Senescence?   Cellular senescence significantly contributes to skin aging by accumulating dysfunctional cells that impair regeneration, promote inflammation, and accelerate tissue degradation. Recent research has highlighted the potential of senolytic and senomorphic agents to target or modulate these senescent cells, aiming to restore skin homeostasis.    This session will explore…
Posted on March 4, 2025
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Skin Challenges 2025 Special Session: Senolytic & Senomorphic Agents – Strategies and Impact on Rejuvenation

Skin Challenges 2025 Special Session: Senolytic & Senomorphic Agents – Strategies and Impact on Rejuvenation

  Why a session dedicated to Senescence?   Cellular senescence is a key driver of skin ageing, contributing to loss of elasticity, impaired wound healing, and chronic inflammation.    Understanding the mechanisms of senescence and developing targeted interventions — such as senolytics to eliminate senescent cells and senomorphics to modulate their effects — are crucial…
Posted on March 4, 2025
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Standardizing Cellular Senescence Research: The MICSE Guidelines

Standardizing Cellular Senescence Research: The MICSE Guidelines

A research article titled “Guidelines for Minimal Information on Cellular Senescence Experimentation In Vivo” introduces the MICSE framework designed to standardize the identification and study of senescent cells in living organisms. These guidelines aim to improve the accuracy of research and deepen the understanding of cellular senescence in health and disease. Key Points: MICSE Guidelines:…
Posted on February 27, 2025
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