
Self-Assembled Nanomaterials for Chronic Skin Wound Healing
Chronic wounds can be caused by several underlying molecular and cellular pathophysiological mechanisms, including poor vascularization, excessive extracellular matrix (ECM) degradation by proteases, decreased growth factor activity, and bacterial infection. More effective wound therapies need to address one or more of these mechanisms to significantly advance wound care. Self-assembled nanomaterials may provide new therapeutic options…