Author: skin_challenges

Patients who undergo skin injuries endure hospital stays, infection and/or succumb to death; therefore, advances in wound healing aim to improve clinical practices underlying macroscale healing to effectively intervene in microscale pathophysiology. As a result, strategies that optimize wound healing have motivated the design of new therapeutic products. In a new report in Science Advances, Benjamin…

Credit: The KonG/Adobe Stock As lovers might vouch, complex nuances of touch, including nearness sans physical contact and gradations of tactile pressure, convey a rich sensory experience and multi-dimensional cognitive pursuits. Intelligent interactions between biological entities or machines and organisms require artificial skins that can perceive fluctuations of intensity and pre-contact proximity. Until now, advances…

The analysis of the role of the mitochondria in oxidative damage and skin aging has been a significant aspect of dermatological research. Mitochondria generate most reactive oxygen species (ROS) which, in excess, are cytotoxic and DNA-damaging and promote (photo-)aging. However, ROS also possesses key physiological and regulatory functions and mitochondrial dysfunction is prominent in several…

The composition of the skin microbiome varies from infancy to adulthood and becomes most stable in adulthood. Adult acne patients harbour an ‘acne microbiome’ dominated by specific strains of Cutibacterium acnes. However, the precise timing of skin microbiome evolution, the development of the acne microbiome, and the shift to virulent C. acnes strain composition during puberty is unknown. Schneider…