From Cellular Mechanisms and Senescence to Regenerative Strategies:
Rethinking Skin Ageing.
The two-day conference in Valencia (November 11–12, 2025) will explore the core biological processes of skin ageing, examining epigenetic regulation, cellular senescence, inflamm’aging, circadian proteomics, and the skin brain body axis before transitioning to cutting-edge regenerative approaches, including microbiome restoration, nanotechnology and NK cell–based senolytic therapies, innovative biomaterials, and smart skincare technologies designed to drive precision and personalized dermatology.

The official agenda for Skin Ageing & Challenges 2025 is now published, featuring an exceptional lineup of international experts, visionary talks, and emerging science at the interface of mitochondria, microbiome, and regenerative skin medicine.
We invite you to discover the program and join us for the Concluding Discussion: Rethinking Skin Ageing: Perspectives and Challenges Ahead.
This closing session will explore key questions shaping the future of skin research:
- Where are we now?
- Where are the targets?
- Can we extend healthy skin?
- Have we forgotten something?
From mitochondria to microbiome, from molecular design to clinical translation this dialogue will define the next frontiers in understanding and intervening in the ageing process.
Join us in Valencia to exchange ideas, discover the latest research, and explore groundbreaking strategies for skin aging and rejuvenation!
As always, we are very much looking forward to meeting you in Valencia.
Prof. Jean Krutmann
President of Skin Ageing & Challenge 2025
IUF – Leibniz Research Institute for
Environmental Medicine, Leibniz
German
