Guiseppe Valacchi

Prof. Giuseppe Valacchi, from the University of Ferrara, Italy will give a strategic presentation about AtmO3 spheric skin damages: the Ox-Inflammation phenomena during Skin Ageing & Challenges congress 2018.

According to Prof. Valacchi: Atmospheric factors such as air pollution (smog, ozone, particulate matter, etc.) have been implicated in premature skin aging and possibly being associated with skin pathologies.  Among the pollutants to which cutaneous tissue is exposed, ozone has been shown to be one of the most noxious. The skin damage caused by ozone exposure is largely attributable to a complex cascade of reactions in the skin initiated by the generation of reactive oxygen species (ROS), which causes oxidative damage to cellular components such as proteins, lipids and nucleic acids. The damaged skin cells initiate inflammatory responses leading to the eventual damage manifested in chronically exposed skin. ROS generation and increased inflammatory mediators leads to positive feedback, oxinflammation, that can further augment the skin damage.  This talk will review summarizes our current knowledge of ozone on skin damage.”

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