Targeting Cellular Senescence Based on Interorganelle Communication, Multilevel Proteostasis, and Metabolic Control

Dr. Maria Amália Cavinato Nascimento, from Institute for Biomedical Aging Research, Leopold Franzens Universität Innsbruck, Austria will join the Skin Ageing & Challenges 2021 Congress to talk about “Targeting Cellular Senescence based on Interorganelle communication, multilevel proteostasis, and metabolic control“.

In fact, cellular senescence, a stable cell division arrest caused by severe damage and stress, is a hallmark of aging in vertebrates including humans. With progressing age, senescent cells accumulate in a variety of mammalian tissues, where they contribute to tissue aging, identifying cellular senescence as a major target to delay or prevent aging. There is an increasing demand for the discovery of new classes of small molecules that would either avoid or postpone cellular senescence by selectively eliminating senescent cells from the body or inactivating/switching damage-inducing properties of senescent cells, such as the senescence-associated secretory phenotype.

Skin Ageing & Challenges 2021
November 10-12, 2021 – Interactive Online Congress