Harnessing the power of extracellular vesicles for wound regeneration
Dr. Hugo Fernandes from University of Coimbra, Portugal will join Skin Challenges 2020 and will give a presentation entitled “Harnessing the power of extracellular vesicles for wound regeneration“.Summary of talk: Extracellular Vesicles (EVs) are key mediators of intercellular communication. Until recently, little was know regarding their therapeutic potential. We and others showed that naive EVs, isolated from different sources (e.g., cord blood mononuclear cells, mesenchymal stem/stromal cells) can accelerate wound healing in various settings. More importantly, we have developed a new platform capable of modulating naive EVs endowing them with improved bioactivity and/or targeting potential. In this talk, we will show how modulated EVs were capable of enhancing wound healing in a diabetic mouse model.